The World Health organization updated the classification of central nervous system tumours in 2016 with more emphasis placed on molecular signature. This has led to widespread adaptation of more targeted therapy in neurosurgery. Primitive Neuroectodermal Tumour has been subdivided leading to the emergence of epidermal tumor with multi-layered rosettes as a separate entity. https://parisnaturalfoodes.shop/product-category/nutrimeno/